Nov 19, 2025 · Discover the specific pharmacological reason why metronidazole works on Giardia. This medication targets the parasite's unique anaerobic metabolism, leading to its …

Aug 28, 2024 · Azoles are one of the most widely used classes of antifungal agents in medical practice today. They have revolutionized the management of fungal infections due to their …

In spite of its recognition as an important human pathogen, there have been relatively few agents used in therapy. This paper discusses each class of drugs used in treatment, along with their …

The anaerobic environment within Giardia facilitates the reduction of metronidazole by specific enzymes. This reduction process converts metronidazole into its active form, which then …

Sep 25, 2025 · The azoles that are available for systemic use can be classified into two groups: the triazoles (fluconazole, itraconazole, voriconazole, posaconazole, and isavuconazole) and …

Feb 20, 2024 · If the patient's stool samples still remain positive for Giardia even after combination therapy, consider an underlying immunodeficiency that may be preventing the …

To help diagnose giardia infection (giardiasis), your doctor is likely to test a sample of your stool. For accuracy, you may be asked to submit several stool samples collected over a period of days.

The azoles are significantly less nephrotoxic than amphotericin B, but are not without side effects. They also demon-strate a number of significant drug interactions.

Nov 25, 2025 · Learn why metronidazole is a primary treatment for Giardia infection. This guide explains its targeted mechanism of action, side effects, and therapeutic role in treating giardiasis.

Azole antifungals work by disrupting ergosterol biosynthesis, a key component of fungal cell membranes. This disruption increases membrane permeability, leading to cell death.