Myc - Wikipedia
The Myc family consists of three related human genes: c-myc (MYC), l-myc (MYCL), and n-myc (MYCN). c-myc (also sometimes referred to as MYC) was the first gene to be discovered in this …
MYC, Metabolism, and Cancer - PMC
The MYC oncogene encodes a transcription factor, MYC, whose broad effects make its precise oncogenic role enigmatically elusive. The evidence to date suggests that MYC triggers selective …
MYC Gene - GeneCards | MYC Protein | MYC Antibody
Nov 14, 2025 · MYC (MYC Proto-Oncogene, BHLH Transcription Factor) is a Protein Coding gene. Diseases associated with MYC include Burkitt Lymphoma and High-Grade B-Cell Lymphoma Double …
The effects of MYC on tumor immunity and immunotherapy
Mar 25, 2023 · The abnormal expression of MYC is one of the most common carcinogenic events in human cancer. MYC modulates immune effector cells and immune regulatory factors in the tumor …
MYC: a complex problem: Trends in Cell Biology
As an oncogenic driver, MYC amplifies global transcription by driving pause release and the early transcription, especially of highly expressed genes. It stimulates replication by facilitating assembly of …
MYC: a multipurpose oncogene with prognostic and therapeutic ...
Aug 9, 2021 · In this review, MYC regulation and the mechanisms by which MYC adjusts cellular functions and its implication in hematologic malignancies are summarized. Further, we also discuss …
MYC function and regulation in physiological perspective
Oct 24, 2023 · MYC interacts with several cofactors, chromatin modifiers, and regulators to direct gene expression. MYC levels are tightly regulated, and deregulation of MYC has been associated with …
The MYC oncogene — the grand orchestrator of cancer growth and …
MYC has two paralogues: MYCL and MYCN. The initially held view was that MYC is ubiquitously involved in human cancers (both haematological and solid), whereas L-MYC is associated with small …
MYC: there is more to it than cancer - PMC
MYC is a pleiotropic transcription factor involved in multiple cellular processes. While its mechanism of action and targets are not completely elucidated, it has a fundamental role in cellular proliferation, …
An Overview of MYC and Its Interactome - PMC
This review is intended to provide a broad outline of the biological and molecular functions of MYC as well as of the larger protein network within which MYC operates.