One small atom can make a big difference in a molecule’s pharmacological properties. Especially if that atom is a nitrogen. Chemists at the University of Oklahoma have now unveiled a new strategy for ...

From left: UChicago chemists Mark Levin, Jisoo Woo, and Tyler Pearson discuss techniques to swap nitrogen atoms in molecules—a change often made by drug discovery chemists. Credit: Julia Driscoll For ...

Catalysts with a metal-nitrogen bond can transfer nitrogen to organic molecules. In this process short-lived molecular species are formed, whose properties critically determine the course of the ...

For years, if you asked the people working to create new pharmaceutical drugs what they wished for, at the top of their lists would be a way to easily replace a carbon atom with a nitrogen atom in a ...