Lysosomes, often reductively referred to as the "garbage disposals" of cells, play a pivotal role in our cells’ digestive systems by getting rid of unwanted materials. Now in a groundbreaking study, ...
CHICAGO (CBS) -- Lysosomes – membrane-bound structures within each cell of humans and all animals – are sometimes known as the cells' "garbage disposals" or "cellular janitors." The structures are ...
A 3D reconstruction showing the inner mitochondrial membrane (red) herniating into a closely associated lysosome (green). The outer mitochondrial membrane is shown in blue and the nucleus is shown in ...
Lysosomes are membrane-bound organelles whose acidic lumen (pH 4.5–5.0) is required for degradation. This luminal acidity is ...
C-terminal fragments of amyloid precursor protein have been blamed for endolysosomal dysfunction in Alzheimer’s disease. Now, scientists led by Wim Annaert at KU Leuven, Belgium, claim that’s because ...
Researchers at the Hospital for Sick Children (SickKids) report that mitochondria depend on a newly discovered recycling mechanism. Their research demonstrates mitochondria can recycle a localized ...
Cancer treatments necessarily target unchecked cell growth, and selectively kill cancer cells while sparing normal cells and avoiding general toxicity in the human body. To develop new treatments for ...
When astrocytes transform from homeostatic to reactive, what goes wrong inside them? Martin Kampmann, University of California, San Francisco, and colleagues blame dysfunctional lysosomes. In a ...
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