Particles (encircled in green) are spaced at a distance from the noise surrounding the nanobeads (purple), which would otherwise obscure them. Sample loss has been a persistent problem in cryo-EM, a ...

In order to expand access to cutting-edge research technology, the University of California, Santa Cruz, is welcoming institutions in the United States and abroad to use its powerful ...

Despite advancements, cryo-EM sample preparation remains a bottleneck, affecting structural biology and protein science through intrinsic disorder challenges.

A massive transmembrane complex, γ-secretase churns out the infamous peptides that can start a person on the path in Alzheimer’s disease. Aβ is produced when the secretase shaves three residues at a ...