Both radiation and temozolomide, a generic chemotherapy treatment in pill form, have meaningful single-modality anti-tumor activity against slow-growing, low-grade gliomas. The randomized phase 3 ...
“We found that the 10-year survival rate was 70% with the combined treatment with temozolomide chemotherapy and radiation, compared to 47% with radiation alone as the initial approach. This discovery ...
We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. Temozolomide with radiation therapy improved 5- and ...
A photo of co-authors from the Department of Neurosurgery, Niigata University, including Dr. Takuya Okada (middle) and Dr. Manabu Natsumeda (right of Dr. Okada). A team led by Dr. Manabu Natsumeda ...
Concomitant radiotherapy with temozolomide significantly improves PFS in IDH-wildtype glioblastoma patients compared to radiotherapy alone. The study involved 244 patients, with 72.5% receiving ...
Adjuvant temozolomide (12 cycles, 5/28-day schedule) after radiotherapy significantly improves overall survival in IDH-mutant, 1p/19q non-codeleted anaplastic astrocytoma compared with radiotherapy ...
Elevated Plasma YKL-40 Predicts Increased Risk of Gastrointestinal Cancer and Decreased Survival After Any Cancer Diagnosis in the General Population Sixty-five eligible adults with newly diagnosed ...
PURPOSE: Temozolomide is a novel oral alkylating agent with demonstrated efficacy as second-line therapy for patients with recurrent anaplastic astrocytoma and glioblastoma multiforme (GBM). This ...
Please provide your email address to receive an email when new articles are posted on . The 3.3-month improvement in median OS in the investigational arm did not reach statistical significance.