Technologies at the Advanced Rodent Transgenics Laboratory include genome editing design and implementation and transgenic ...

Using CRISPR-based technologies, the MoDeL team introduces precise genetic modifications in mice, enabling researchers to uncover how mammalian genes maintain health and contribute to disease.

In the late 2000s and early 2010s, neurogeneticist Vivek Kumar, then a postdoctoral researcher at the University of Texas Southwestern Medical Center, screened thousands of randomly mutagenized mice.

New research suggests that the commonly used ‘lab mouse’ may display behaviors entirely distinct from their wild-derived counterparts, prompting new considerations for the future of animal-based ...