Liquid biopsy advances could yield new tool for detecting lung cancer mutations

In Brazil, the early detection of genetic alterations in lung cancer through liquid biopsies could be a valuable tool for ...
The American Journal of Managed Care

Multi-Hit TP53 Mutations Linked With Poor Outcomes in MPN, AML

Multi-hit TP53 mutations are linked to poor survival in both MPN and AML, with median OS ranging from 4.8 to 11.6 months. Factors such as ASCT, pre-transplant therapy response, and concurrent TET2 or ...
The American Journal of Managed Care

Managing Germline Mutations in Hereditary Breast Cancer Risk

Hereditary breast cancer results from inherited mutations, primarily in BRCA1 and BRCA2, increasing lifetime cancer risk. Additional genes like TP53, PTEN, PALB2, CHEK2, and ATM also contribute to ...
STAT

Genetic variant appears to protect some people against certain blood cancers

Researchers found a genetic variant that appears to protect against the development of CHIP, a phenomenon that can lead to ...