Fei Chen and Chenlei Hu at the Broad Institute of MIT and Harvard have developed a new imaging-free spatial transcriptomics technology that tracks the diffusion of DNA barcodes between beads in an ...

A wave of spatial transcriptomics studies has produced gene-expression atlases that span entire organs and whole organisms, from mouse embryos to the roundworm C. elegans to 31 human tissues. These ...

To study biological processes, scientists often take snapshots of the molecules in cells, such as proteins and nucleotides, at specific points in time. In spatial biology, they can leverage molecular ...

Challenges and Prospects. Challenges and prospects faced by spatial transcriptomics itself and its application to the musculoskeletal system. AI Artificial intelligence, FFPE Formalin fixed and ...

Spatial transcriptomics is transforming how scientists see biology—literally—by mapping gene activity in its original location inside tissues. From decoding tumor architecture to charting entire ...

Foundation models (FMs), which are deep learning models pretrained on large-scale data and applied to diverse downstream tasks, have transformed natural language processing and multimodal AI. However, ...

Spatial ribonucleic acid (RNA) transcriptomics measures gene expression while preserving each molecule’s coordinates in intact tissue, tying transcripts to histology and local microenvironments.

A group of a few dozen colorful translucent 3D blobs, many of which overlap, contain brightly colored dots against a black background. Three-dimensional transcriptomics data from an instrument ...

10x Genomics’ facility at 5500 Stoneridge Mall Road Pleasanton, CA, one of the company’s three sites in the San Francisco suburb. 10x Genomics has joined with two licensor partners to administer a ...