Microscopy continues to transform the life sciences. Here are five recent breakthroughs made possible by the technique.

Example of super-resolution microscopy: The image shows how the Discrete Molecular Imaging (DMI) technology visualizes densely packed individual targets that are just 5 nanometer apart from each other ...

Researchers have reported a sample-prior-based approach to point spread function decoupling that improves system ...

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...

Electron microscopy has become a vital tool in structural biology, enabling researchers to visualize biological macromolecules at near-atomic resolution. Recent advances have transformed it from a low ...

Researchers have developed a new microscope that can visualize the optical response of surfaces at an unprecedented spatial resolution of one nanometer. This paves the way for optical microscopy of ...

To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

Microscopes have long been scientists’ eyes into the unseen, revealing everything from bustling cells to viruses and nanoscale structures. However, even the most powerful optical microscopes have been ...

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

Computational fluorescence microscopy (CFM) requires accurate point spread function (PSF) characterization for high-quality ...