A surprising amount of the DNA sequence in the genes of humans and other higher organisms ends up on the cutting-room floor, so to speak, spliced out by the cellular machinery that turns genetic code ...

The arrival of next-generation sequencing (NGS) technology has revolutionized the field of genomics and expanded the scope of scientific inquiry to sequence datasets from multiple genomes and ...

An international research team has succeeded in developing a new version of RNA building blocks with higher chemical reactivity and photosensitivity. This can significantly reduce the production time ...

Microarray technology has come of age as a powerful approach to revealing the genome and its dynamic expression through the application of gene-hybridization or gene-expression microarrays. While the ...

Biochips (microarrays) are modern analytical tools that allow thousands of individual detections to be performed simultaneously in a small amount of sample material. A team led by Mark Somoza from the ...

One advantage of Northern blotting is the ease with which comparative analyses can be carried out, as researchers can run RNA samples representing different developmental time points, tissues, or ...

This work was supported by funding from New Zealand Ministry of Business Innovation and Employment, Research Trust of Victoria University of Wellington and The Hugh Green Foundation. The recent award ...

A full-size, high-density RNA microchip is about the size of a fingernail and can contain up to 780 000 unique RNA sequences, each occupying a ~14 x 14 μm² area. The presence and the quality of the ...