Chemists have developed an organic catalyst that can drive reactions using pyruvate -- a key biomolecule in many metabolic pathways -- that are difficult and complicated to achieve using conventional ...

Pyruvate is produced by glycolysis, a process in which carbohydrates are broken down to create energy. Calcium pyruvate is a popular supplement that many people use primarily for its purported weight ...

Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria, the 'powerhouses' of our cells, allows us to make the fuel we need from sugars, a ...

Having considered localization of respiratory functions in mitochondria and in prokaryotic cells, it's time to return to the ...

Scientists led by a team at the Medical Research Council (MRC) Mitochondrial Biology Unit, University of Cambridge, have worked out how a molecular machine found in mitochondria—the “powerhouses” of ...

A team of researchers at the University of Delaware has discovered a new function for an enzyme that has long been known to have a central role in bacterial metabolism. Maciek Antoniewicz, Centennial ...

The Food and Drug Administration (FDA) has accepted for Priority Review the New Drug Application for SL1009 (sodium dichloroacetate oral solution) for the treatment of pyruvate dehydrogenase complex ...

Scientists develop a new organic catalyst system, inspired by enzymes, that improves the process of making organic molecules from an essential biomolecule called pyruvate. Scientists have developed an ...