The cerebellum is instrumental in coordinating movement and refining motor control through intricate neuronal circuitry, with Purkinje cells serving as the central integrators of sensory inputs and ...

In 1906, Spanish scientist Santiago Ramón y Cajal won the Nobel Prize for his pioneering studies of the microscopic structures of the brain. His famous drawings of Purkinje cells in the cerebellum ...

Purkinje cells were discovered by Jan Evangelista Purkyně in 1839 and famously illustrated by Santiago Ramón y Cajal in 1899. This Ramón y Cajal drawing shows cerebellar Purkinje cells (A) and granule ...

MicroRNAs are essential for Purkinje cells to develop their characteristically elaborate dendritic arbors. When Scripps Research scientists temporarily turned off microRNA function during development, ...

Purkinje cell drawing by Santiago Ramón y Cajal circa 1899. Scientists at the annual 2014 Society for Neuroscience meeting (November 14-19) in Washington D.C. presented unpublished research that links ...

A new McGill University study has found a direct link between age-related declines in neuron activity in the cerebellum and worsening motor skills, including gait, balance and agility. While it is ...

A new McGill University study has found a direct link between age‑related declines in neuron activity in the cerebellum and worsening motor skills, including gait, balance and agility. While it is ...

As the brain ages, it loses cells. Researchers have predominantly focused on the effects of cell death in brain areas responsible for cognition, but the cerebellum, most well-known for coordinating ...

Although the prevailing wisdom among neuroscientists is that Purkinje cells have just one primary dendrite that connects with a single climbing fiber from the brain stem, new research shows that ...