tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

The ribosome, that protein-making machine, relies on other, smaller machines. For example, it works in concert with a mechanism that supplies amino-acid-carrying tRNAs, including tRNAs that require ...

An international team of researchers including scientists from The Australian National University (ANU) have developed a way ...

Loss of TRMT10A led to a decrease in the levels of initiator methionine tRNA (tRNA iMet) and a specific glutamine tRNA (tRNA Gln). This reduction weakened the initiation of protein synthesis for ...

An international team of researchers including scientists from The Australian National University (ANU) have developed a way to reveal the smallest ...

Aminoacyl-tRNA synthetases (aaRSs) are ubiquitous enzymes that provide the critical link between the genetic code and protein biosynthesis. By precisely catalysing the attachment of amino acids to ...

Researchers say discoveries could expand the CRISPR toolbox and lead to more efficient, rapid diagnostic tools for detecting COVID-19, influenza, and RSV.

Scientists at the University of California, Santa Cruz, have trapped the ribosome, a protein-building molecular machine essential to all life, in a key transitional state that has long eluded ...

During protein synthesis, the genetic information stored in DNA is first transcribed into mRNA. The mRNA then travels to the ribosome, where translation occurs. Here's how anticodons facilitate the ...

Prostate cancer is the second-most common cancer in men. A new study from Thomas Jefferson University uncovered a new ...