Clinicians and researchers have suspected for years that an aggressive, less-common form of multiple sclerosis (MS) is likely a distinct form of the disease. Now, new research conducted using a more ...

Researchers demonstrate the relationship between the rate of cognitive fatigue in MS and microstructural brain changes. The findings promise to advance development of clinical interventions for ...

Immunological memory - the ability to respond to a previously encountered antigen, or foreign substance, with greater speed and intensity on re-exposure is a hallmark of adaptive immunity. Innate ...

Multiple sclerosis (MS) is the result of the immune system mistakenly attacking the brain and the spinal cord, causing tissue damage (lesions) throughout. While the underlying mechanism of lesion ...

Systematic analyses of the complex interplay of genetic and environmental factors that regulate immune cells are key in unraveling the pathophysiology of multiple sclerosis (MS). However, the ...

New research shows early Multiple Sclerosis brain damage is dynamic and reversible. Myelin swellings can shrink and disappear ...

A new study reveals how Epstein-Barr virus may provoke immune cells to attack the brain, offering fresh hope for treating multiple sclerosis.

Collaborating scientists at the Karolinska Institute and at Stockholm University used a technology called in situ sequencing (ISS) to help reveal at the cellular level how lesions in multiple ...

Iron dysregulation contributes to MS progression through oxidative stress, ferroptosis, and immune activation, affecting neuronal and immune cell function. Both iron overload and deficiency exacerbate ...

The Marburg variant of multiple sclerosis is extremely rare but also the most severe. Life expectancy has been weeks or months, but advances in treatment have led to an improved outlook. Multiple ...