While the genes involved can differ, this example illustrates how most cancers arise. Accumulated DNA mutations, acquired either over time (ageing naturally leads to some DNA mistakes) or from ...

Imagine a tiny superhero inside every cell of your body whose job is to stop damaged cells before they turn dangerous. That superhero is a gene called TP53, and for decades scientists have known it as ...

A systematic review of 52 scientific papers submitted to a world-leading clinical genetics journal from multiple scientists ...

Cancer begins when mutations in specific genes override the body’s built-in controls on cell division, allowing rogue cells ...

Many women breathe a sigh of relief when they test negative for BRCA gene mutations, which raise the risk for breast, ovarian and other cancers. But that's not the end of the hereditary risk story.

A rare mutation on the BCL6-corepressor gene correlated with worse overall survival in patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). However, allogenic stem cell ...

For years scientists have tried to find a gene for conditions like schizophrenia, Alzheimer’s and autism. But the real source could lie in a much more complex genetic puzzle. When Mike McConnell ...

Not all cancer mutations are equal. A Nature Genetics study led by Dr. Derya Deniz Özdemir (Koç University) shows that even small differences in a ...

Two large-scale studies provide new data on genes, inherited variations, and de novo mutations associated with autism spectrum disorder (ASD). Some of them are also associated with other neurological ...