Nature

Multiplexed ion beam imaging of human breast tumors

Immunohistochemistry (IHC) is a tool for visualizing protein expression that is employed as part of the diagnostic workup for the majority of solid tissue malignancies. Existing IHC methods use ...
Nature

Multiplexed ion beam imaging analysis for quantitation of protein expresssion in cancer tissue sections

Part of developing therapeutics is the need to identify patients who will respond to treatment. For HER2-targeted therapies, such as trastuzumab, the expression level of HER2 is used to identify ...