Determining true HER2 status in breast cancers with polysomy using alternative chromosome 17 reference genes: Implications for trastuzumab therapy. Background: Systemic chemo- and chemoradiation ...

While microarray technology is broadening its applications in genomics and proteomics, the technique remains a vibrant contributor in the area of gene expression. Much of the overall developmental ...

Recent studies have shown variation in the gene-expression profile and phenotype of microglia across brain regions and between different age and disease states. But the molecular mechanisms that ...

DNA methylation is an epigenetic modification characterized by the addition of a methyl group to a DNA molecule. As DNA methylation is implicated in both normal biological processes, such as ...

The Genomics Core offers a variety of microarray analysis options for DNA and epigenetic studies. The Illumina BeadArray technology combined with the Illumina iScan Array Scanner allows for analysis ...

Precision medicine experts take into account several factors when developing appropriate treatments for diseases, including population risk or incidence, the underlying genetic cause and potential ...

In the central nervous system, microglial cells play critical roles in development, aging, brain homeostasis, and pathology. Recent studies have shown variation in the gene-expression profile and ...

DNA Methylation: Timekeeper of Biological Age from thescientistllc on Vimeo. Cellular senescence, telomere shortening, and changes in gene expression have been well documented to contribute to the ...