The development of cancer is not a process triggered immediately by the emergence of an oncogenic mutation. There is growing ...

The MYC oncogene family plays an important role in neoplastic disease, and has been extensively studied over decades. Evidence showing the N-terminal and C-terminal regions of MYC can function as a ...

Novel Treatment Targets in Sarcoma: More Than Just the GIST MYC has proven to be a highly potent oncoprotein when it is overexpressed, but is also a pleiotropic transcription factor essential for ...

Chemotherapy drugs are designed to shatter tumor DNA so thoroughly that cancer cells cannot survive. But one of the most common cancer-driving proteins, MYC, appears to run a quiet rescue operation in ...

For decades, oncologists have watched a frustrating pattern repeat itself. Tumors fueled by the MYC protein, one of the most commonly hijacked genes in human cancer, often shrug off the very ...

Scientists found a protein that may help tumors repair DNA damage, revealing a new challenge for cancer treatment.

MYC family genes are essential for the human organism. According to current knowledge, they regulate the expression of most cellular genes. Misregulation of MYC proteins significantly contributes to ...

Northwestern Medicine investigators have discovered a new combination approach that may improve the efficacy of MYC inhibitor drugs for treating aggressive and treatment-resistant cancers, according ...

Cancer researchers have discovered surprising new functions for a protein called MYC, a powerful oncogene that is estimated to drive the development of almost half a million new cancer cases in the US ...

Sperm – in theory, you only need one good one to get the job done. Nevertheless, the average pair of human testicles is estimated to crank out about a trillion of these little cells over a lifetime, ...