Ganji M et al., and Fudenberg G et al., postulated that the SMC family of ATPases, such as condensin and cohesion, extrude DNA into large loops. Energy from ATP hydrolysis helps the SMC proteins to ...
Leonid A. Mirny is at the Institute for Medical Engineering and Science and the Department of Physics, Massachusetts Institute of Technology, Massachusetts 02139, USA. Cells neatly compact their ...
How does a meter-long strand of DNA fit inside a cell without forming a tangled mess? This accomplishment comes courtesy of structural maintenance of chromosomes (SMC) proteins, which orchestrate the ...
To separate replicated sister chromatids during mitosis, eukaryotes and prokaryotes have structural maintenance of chromosome (SMC) condensin complexes that were recently shown to organize chromosomes ...
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