The transient receptor potential (TRP) ion channels comprise a diverse superfamily of cation channels that play pivotal roles in sensory transduction, enabling organisms to detect a wide range of ...

Johns Hopkins scientists reveal that “inactive” GluD brain proteins regulate neuronal communication and open up new ...

G protein-coupled receptors (GPCRs) constitute one of the largest families of membrane proteins and play a pivotal role in translating extracellular signals into diverse intracellular responses. A key ...

The ability to accurately detect heat and pain is critical to human survival, but scientists have struggled to understand on a molecular level exactly how our bodies sense these potential risks. Now, ...

In the late 1950s, dopamine was recognized as a neurotransmitter in its own right. A specific functional role for dopamine was suggested by the demonstration of its uncharacteristic distribution in ...

Researchers have unraveled the complex biological phenomena that enable the sensing of heat and pain. The ability to accurately detect heat and pain is critical to human survival, but scientists have ...