Histone Kla regulates tumor angiogenesis by affecting the levels of downstream HIF1-ɑ and Vegf. In non-histone proteins, YY1-Kla influences FGF2, and Sema3A-Kla affects HIF1-ɑ, both contributing to ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

What is the histone code? Different chemical marks, such as acetylation, methylation, or phosphorylation, are made to numerous residues on the N-terminal tails of histone proteins. Some posit that ...

Researchers showed that in C. elegans, the protein MBD-2 regulates genes through repressive histone marks rather than DNA ...

If parent cells and their daughter cells are to share a stable identity, parent cells must divide—and replicate their DNA—while ensuring that their histones are distributed properly to their daughter ...