The primary rationale for middle-down proteomics is the need for high-confidence proteoform analysis that is also scalable. A proteoform is defined by its full complement of modifications and sequence ...
1 Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA 2 Department of Chemistry, Princeton University, Princeton, NJ 08544, USA Histone post-translational modifications ...
This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...