This webinar will look at the principles of the assays available to monitor heparin. The most frequent assay that is used is the activated partial thromboplastin time (aPTT). This assay is readily ...

Background: Unfractionated heparin (UFH) has been used clinically for 5 decades. Despite being a cornerstone of anticoagulation, UFH is limited by its unpredictable pharmacokinetic profile, which ...

Factor deficiency or inhibition. The possible causes of the isolated prolonged aPTT in this case include factor deficiencies and factor inhibitors. Prolongation of both the PT and aPTT suggests ...

Sponsored by: Diagnostica Stago, Inc. Ever since the introduction of the direct oral anticoagulants (DOACs), such as apixaban and rivaroxaban, laboratory staff and clinicians have been confronted with ...

A 47-year-old diabetic woman, weighing 90.5 kg, with no previous history of abnormal bleeding was diagnosed with acute myelogenous leukemia (subtype M2). She was treated with two courses of cytarabine ...

We evaluated two patients in whom heparin-induced thrombocytopenia developed after orthopedic surgery, with the delayed-onset type in Patient 1 and the spontaneous type in Patient 2 (Figure 1). The ...