Older people may be at greater risk of developing pancreatic cancer and have poorer prognoses because of age-related changes in cells in the pancreas called fibroblasts, according to new research.
A study provides insights into the diversity of cancer-associated fibroblasts in white and black skin cancer and describes their different immunomodulatory roles in the tumor environment. The results ...
A new study led by investigators from the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins Bloomberg School of Public Health, and the Bloomberg~Kimmel Institute for Cancer Immunotherapy may ...
In a recently published study, researchers at Fox Chase Cancer Center revealed for the first time that cancer cells can evade anti-cancer drugs by entering and surviving within bone marrow fibroblasts ...
A study at MedUni Vienna's Department of Dermatology provides insights into the diversity of cancer-associated fibroblasts in white and black skin cancer and describes their different immunomodulatory ...
Cancer-associated fibroblasts (CAFs) are crucial in melanoma metastasis, influencing tumor microenvironments and patient outcomes, especially in immunotherapy contexts. Single-cell RNA sequencing ...
A working model showing that CAFs exhibit profound amino acid reprogramming, especially the production of glycine, in CRC. CRC cell‐derived TGF‐β1 activates de novo glycine synthesis in CAFs, ...
Daniel Zabransky, M.D., Ph.D., in the lab. The study, published online Feb. 8 in Cancer Research, provides clues as to why pancreatic cancer is more common and aggressive in older people. It may also ...
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