Fibrin hydrogel, an oft-used two-dimensional scaffold for in vitro cell culture, was recently functionalized to grow human induced pluripotent stem cells (hiPSCs) in three dimensions. This advance ...

The research team used model spinal cord injuries in rats for their purposes. As a result, it was found out that therapy by adipose-derived mesenchymal stem cells combined with fibrin matrix ...

PNAS is the world's most-cited multidisciplinary scientific serial. It publishes high-impact research reports, commentaries, perspectives, reviews, colloquium papers, and actions of the Academy. In ...

A new chimera protein creates a potent, xeno-free fibrin scaffold with strong cell adhesion, paving the way for reproducible and medically applicable stem cell therapies. Construction of the ...

Osaka, Japan - Scientists at The University of Osaka have developed a novel hydrogel that enables the efficient, three-dimensional (3D) culture of human induced pluripotent stem cells (iPSCs). By ...