Non-immune cells play a crucial and often underappreciated role in host defense against invading pathogens. Beyond serving as passive physical barriers, ...
The research team engineered CD8+ Jurkat T cells to express SVAR16, a human TCR with intermediate-to-high 2D affinity for the SARS-CoV-2-derived epitope HLAA2:01–YLQ, using lentiviral transduction.
Regulatory T cells protect the body from misdirected or overly excited immune responses. A new study highlights previously unknown characteristics of these cells that could guide the development of ...
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