This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role in understanding the complex interplay between genetics and the environment ...

Epigenetics, the study of changes in gene expression that are not caused by alterations in the DNA sequence, has emerged as a key player in the development and severity of type 2 diabetes. Epigenetics ...

Researchers have discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating epigenetic switch that kick-starts genes in early embryonic development. This finding ...

The team of Professor Christof Niehrs at the Institute of Molecular Biology (IMB) in Mainz, Germany, has discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating ...

Do epigenetic changes cause type 2 diabetes, or do the changes occur only after a person has become ill? A new study provides increased support for the idea that epigenetic changes can cause type 2 ...

Machine learning models reveal that histone marks are predictive of gene expression across human cell types and highlight important nuances between natural control and the effects of CRISPR-Cas9-based ...

Maternal prenatal stress related to natural and human-made disasters can lead to epigenetic modifications in offspring, ...

Type 1 diabetes is an autoimmune disease in which the immune system destroys the body’s own insulin-producing beta-cells in the pancreas, leaving patients with a lifelong dependency on external ...

Children with a family history of type 1 diabetes (T1D) have an increased risk of developing the disease. However, children born to mothers with T1D are less likely to develop the disease than those ...