Increased expression of the Ang‐II (Angiotensin II) precursor AGT in aged astrocytes lead to increased Ang‐II signaling from aged astrocytes to endothelium, thus increasingblood–brain barrier (BBB) ...
Among the body's most crucial protective features are the brain barrier systems, including the blood-brain and ...
Senescent "zombie" cells are essential architects required to build and maintain the brain's protective barriers.
SARS-CoV-2 infection extends beyond the respiratory epithelium to target the vascular endothelium through ACE2 binding. This leads to activation of endothelial cells, disruption of barrier function ...
Among the body's most crucial protective features are the brain barrier systems, including the blood-brain and blood-cerebrospinal fluid (CSF ...
Sepsis, a life-threatening systemic inflammatory response triggered by infection, has long challenged clinicians with its persistently high mortality (up to 40-50% in septic shock). At the heart of ...
A polygenic risk score (PRS) based on genes associated with endothelial cell function identifies patients at a higher risk of coronary artery disease, according to a new study. The risk score, which ...