The numerous cells that make up mammalian tissues are surrounded by an intricate network of proteins known as the extracellular matrix (ECM). Together, these proteins provide cells with a structural ...

The promise of adoptive T-cell therapies—immunotherapy in which T cells are collected from a patient, enhanced, and reinfused—is growing, especially against blood cancers. However, a better ...

"T cells that experienced a more elastic collagen matrix were more likely to develop into 'effector-like T cells,' whereas T cells that experienced a more viscous ECM matrix rather became 'memory-like ...

(Nanowerk News) The successful campaign of adoptive T cell therapies, a type of immunotherapy in which immune T cells are collected from a patient, enhanced outside of the body, and reinfused back ...

UK biotech Engitix has raised a $25 million series A extension from existing investor Netherton Investments, investing on behalf of BlueCrest Capital Management co-founder Mike Platt. The funding will ...

Sarcopenia—reduced muscle mass, strength, and function—is often associated with aging and frequently impacts quality of life in the elderly. Individuals with sarcopenia are also prone to further ...

In a recent study published in Nature, researchers reveal a novel mechanism by which hypothalamic inflammation drives fibrotic remodeling in perineuronal nets (PNNs), a specialized extracellular ...