Potential autoimmune diseases therapies that target dendritic cells aim to either inhibit immunogenic dendritic cell functions or support their tolerogenic potential (Figure 2). Most strategies ...

Using retrospective clinical data and in-depth lab studies, researchers have discovered that vitamin E can enhance immunotherapy responses by stimulating dendritic cells in the tumor. Combining a ...

Cancer immunotherapy is a strategy that turns the patient’s own immune cells into a “search-and-destroy” force that attacks the tumor’s cells. The “search” immune cells are the dendritic cells, which ...

A recent study reveals that inhibiting certain adhesion receptors on the surface of dendritic cells, the main antigen-presenting cells of the immune system, enhances antitumor responses. A recent ...

Immuno-oncology is a promising treatment approach that stimulates the immune system to detect and attack cancer cells. “We’ve seen an initial wave of checkpoint inhibitors and systemic agents that can ...

The immune system consists of inflammatory and regulatory T cells (Tregs) that promote or dampen immune activity, respectively. These cells react to specific antigens that specialized cells like ...

The immune system must be able to quickly attack invaders like viruses, while also ignoring harmless stimuli, or allergies can result. Immune cells are known to ignore or "tolerate" molecules found on ...