Drs Ursula A. Matulonis and Joyce F. Liu discuss targeting DNA damage and repair and replication stress in endometrial cancer. Drs Ursula A. Matulonis and Panagiotis A. Konstantinopoulos discuss ...
According to the researcher, significant differences were found, for example, in the onset and duration of DNA replication and in the production of proteins that regulate the cell cycle. These ...
Researchers at The University of Texas MD Anderson Cancer Center have developed a new imaging method, known as RF-SIRF, that quantitatively detects and maps reversed DNA replication forks with ...
Every day, billions of cells in your body divide, helping to replace old and injured cells with new ones. And each time this happens, your entire genetic library—your genome, which totals more than 3 ...
Cancer cells mount an instant, energy‑rich response to being physically squeezed, according to a study published in the journal Nature Communications. The surge of energy is the first reported ...
Researchers at Oregon Health & Science University have identified a previously unrecognised role for the cancer-associated ...
WEE1 functions as a checkpoint gatekeeper; inhibition forces cell-cycle progression despite unrepaired DNA damage, leveraging tumor replication stress and p53/repair deficits to induce mitotic ...
For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event for DNA to be the molecule that codes all life. A new study from King ...
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