New analytical methods developed at Baylor College of Medicine and collaborating institutions have increased our ...
EMERYVILLE, Calif.--(BUSINESS WIRE)--Profluent, the AI-first protein design company, today announced Protein2PAM, the first in a series of AI models that will broadly focus on protein-DNA interactions ...
Scientists discover a 'Goldilocks' zone for DNA organization, opening new doors for drug development
In a discovery that could redefine how we understand cellular resilience and adaptability, scientists have unlocked the secret interactions between a primordial inorganic polymer of phosphate known as ...
Extrachromosomal DNA (ecDNA) is a unique form of circular DNA that exists outside of normal chromosomes. Found exclusively in tumor cells, it often carries cancer-promoting genes (oncogenes) and is ...
Tunable DNA hairpin springs stretch millions of protein copies under piconewton tension, enabling bulk biochemical discovery of binding partners invisible to single-molecule techniques. (Nanowerk ...
An asymmetric kleisin path breaks the symmetry of the SMC homodimer, ensuring unidirectional DNA translocation via a segment capture mechanism.
Scientists have uncovered a previously unknown type of molecular motion inside DNA-based droplets: instead of spreading randomly, guest molecules advance in an organized wave. This surprising ...
New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human ...
Most fat stores energy; the body's brown fat does the opposite. Unlike the white fat that accumulates just under our skin, ...
This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...
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