Scientists at the University of Osaka have developed a novel hydrogel that enables the efficient, three-dimensional (3D) culture of human induced pluripotent stem cells (iPSCs). By creating a unique ...

Attrition in the therapeutic pipeline can often be associated with the lack of translational efficacy from the pre-clinical phase to the clinic. Organoids demonstrate the significant potential to ...

The shift towards utilizing complex organ-like structures developed from stem cells or tissue samples is becoming essential; these organoid models are leading the way to next-generation, animal-free ...

The XF-DISC surface was smooth, with a root mean square (RMS) roughness (R q) less than 1 nm, as confirmed by atomic force microscopy (AFM) (Fig. 2f). The results of the quantitative analysis of ...

The limiting factor in the current state-of-the-art bioengineering of human tissues/organoids in vitro is the lack of functional vasculature that would support growth, metabolic waste removal, and ...

A new chimera protein creates a potent, xeno-free fibrin scaffold with strong cell adhesion, paving the way for reproducible and medically applicable stem cell therapies. Construction of the ...