There is a growing demand for non-invasive insights into the complex three-dimensional subcellular dynamics within living tissues on the frontier of biological research. To achieve simultaneous ...

Existing super-resolution techniques still face considerable challenges in complex deep tissue environments. For example, Stimulated Emission Depletion (STED) microscopy relies on a doughnut-shaped ...

What is Structured Illumination Microscopy? Structured Illumination Microscopy (SIM) is a super-resolution fluorescence microscopy technique that allows for imaging beyond the diffraction limit of ...

This is especially true when studying intricate details beyond the optical resolution limit using structured illumination microscopy (SIM). SIM uses multiple images acquired under structured ...

Biologists are very interested in how proteins, lipids and other compounds are organized and interact in systems. Very few organizational details can be gained by using standard transmission-based ...

Researchers have incorporated a swept illumination source into an open-top light-sheet microscope to enable improved optical sectioning over a larger area of view. The advance makes the technique more ...

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

CrestOptics S.p.A., a manufacturer of high-end microscopy solutions and advanced systems for fluorescence microscopy, and Tomocube, a leader in holotomography (HT) technology, today announced a ...

Today's super-resolution microscopes have made it possible to observe the nanoscale world with unprecedented detail. However, they require fluorescent tags, which reveal structural details but provide ...