Species: Mouse Genes: Gba1 Modification: Gba1: Knock-In Disease Relevance: Parkinson's Disease Strain Name: Gba1 tm4Ggb Genetic Background: C57BL6, but may be mixed with 129Sv or FVB depending on the ...
This knock-in (KI) mouse model was generated by introducing a D427V point mutation into exon 10 of the mouse Gba1 (glucosidase, beta, acid 1) gene, which corresponds to the human D409V mutation (The ...
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