Chemists from ETH Zurich have found a way to produce poorly soluble proteins by caging a uniquely reactive boron compound. This method opens up new possibilities for the synthesis of tailored protein ...

Many of the “star proteins” of modern medicine—including signaling proteins, protein hormones, and the membrane receptors that make up roughly 60% of today’s drug targets—share an inconvenient trait: ...

A novel study uncovers how a subtle chemical tweak transforms the naturally occurring phytotoxin into a powerful molecular glue, 12-deoxyfusicoccin (12-dFC), that locks 14-3-3 proteins onto the ...

A developer of programmable medicines that combine generative artificial intelligence (AI) and high throughput chemical protein synthesis became Flagship Pioneering’s latest startup to emerge from ...

Many of the key proteins for modern medicine and science are poorly soluble. These include numerous signalling proteins and protein hormones, as well as all of the receptors anchored in the cell ...

New research reveals that subtle chemical changes to proteins after synthesis play a critical role in determining ...

The article provides a comprehensive review of the current progress and future prospects of high-pressure-driven chemical synthesis, offering constructive guidance for the design and development of ...

In the earliest phase of creating human proteins, the protein complex NAC performs an essential task by starting the first steps toward folding proteins into their correct three-dimensional structures ...

One of life's many mysteries is how it ended up choosing only a set of 20 amino acids to build proteins for its wide catalog of organisms, from single-celled bacteria to behemoth whales. From a ...

Researchers have developed AI-driven mobile robots that can carry out chemical synthesis research with extraordinary efficiency. Researchers show how mobile robots that use AI logic to make decisions ...