St. Jude Children's Research Hospital scientists have identified previously unknown functions of the enigmatic enzyme caspase-6. The findings show that caspase-6 is a key regulator of innate immunity, ...
Caspases are a family of cysteine proteases central to the regulation of programmed cell death and inflammatory processes. They exist as inactive zymogens that are activated via proteolytic cleavage ...
Researchers from Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine of The University of Hong Kong (HKUMed) revealed insights into the mechanism of how ...
Caspase-1 triggers programmed necrosis called pyroptosis by gasdermin-D (GSDMD) cleavage. GSDMD-deficient cells are, however, susceptible to caspase-1-mediated cell death. Researchers at Kanazawa ...
Researchers have revealed insights into the mechanism of how coronaviruses including SARS-CoV-2, SARS-CoV-1, and MERS-CoV exploit a host protease called 'cysteine-aspartic protease 6' (caspase-6) for ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results