RNA-binding proteins use a dual binding mechanism involving zinc finger (ZnF) domains and intrinsically disordered regions (IDR), reports a new study from the Institute of Science, Tokyo, Japan. Using ...
Deciphering the spatial, temporal and chemical complexity of RNA molecules in living systems is key to understanding gene regulation at the molecular level. Recent advances in imaging, molecular ...
This figure depicts how bridge recombinases have a dual targeting capability that enable these systems to insert new genetic material, delete unwanted regions, or flip existing DNA segments all in a ...
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Scientists reveal functional RNA splitting mechanism behind origin of type V CRISPR systems
CRISPR-Cas systems are adaptive immune systems found in prokaryotes that defend against invading nucleic acids through CRISPR RNA-guided cleavage. Type V CRISPR-Cas (Cas12) systems, in particular, ...
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