Biological complexity is often masked by bulk sequencing and microarray techniques, which provide an average snapshot of how cells work. In contrast, single-cell sequencing technology allows ...

Dissociating tissues into single cells is a core laboratory technique and vital for widely used applications such as next-generation sequencing or flow cytometry. Scientists who employ tissue ...

Learn how mapping gene-control switches in an ancient sea anemone reveals how identical DNA can produce many different cell types.

Biliary tract cancers (BTCs) are notably aggressive and present significant treatment challenges within the realm of gastrointestinal malignancies. A primary impediment to enhancing patient outcomes ...

Single cell gene expression studies often rely on single-cell RNA sequencing (scRNA-seq) alone. While scRNA-seq reveals which genes are turned on, it does not capture protein expression or changes to ...