Left: Imaging of lamin A/C structures in a physically expanded nucleus from an individual with progeria. Right: Same, but with 3D genomic reads overlaid in their original spatial locations, colored by ...

Link found between super-agers, or people with exceptional longevity, to inherited DNA from Ice Age hunter-gatherer ...

Deep within the intricate world of cellular biology, scientists at Weill Cornell Medicine have made a remarkable discovery about aging that could transform our understanding of human longevity. Their ...

New research reveals how naked mole-rats repair DNA, enhancing genome stability. This discovery could offer a blueprint for human anti-aging and extended healthy lifespan.

Using patient data from several banks of genomics data, researchers at UC San Diego were able to make similar predictions of aging using either mutations or epigenetic modifications. Their results ...

This model of the nucleus with nucleolus (pink) shows how ribosomal DNA is correctly repaired in young cells. In old cells with enlarged nucleolus, however, DNA repair is inaccurate leading to faster ...

As people grow older, their immune systems do not simply slow down, they often become locked into a simmering, ...

Yuan He aims to understand how cells read and repair their genomes. His research encompasses two primary areas: transcription, in which genetic information is copied from DNA into messenger RNA, and ...